Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM47589
Substrate
n/a
IC50
1680±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM47589
Synonyms:
1-Ethyl-6-fluoro-4-oxo-7-{N'-[1-phenyl-meth-(E)-ylidene]-hydrazino}-1,4-dihydro-quinoline-3-carboxylic acid | 1-ethyl-6-fluoranyl-4-oxidanylidene-7-[2-(phenylmethylidene)hydrazinyl]quinoline-3-carboxylic acid | 1-ethyl-6-fluoro-4-oxo-7-[2-(phenylmethylene)hydrazinyl]-3-quinolinecarboxylic acid | 7-(2-benzylidenehydrazinyl)-1-ethyl-6-fluoro-4-oxoquinoline-3-carboxylic acid | 7-(N'-benzalhydrazino)-1-ethyl-6-fluoro-4-keto-quinoline-3-carboxylic acid | 7-[(N''E)-N''-benzalhydrazino]-1-ethyl-6-fluoro-4-keto-quinoline-3-carboxylic acid | 7-[(N'E)-N'-benzalhydrazino]-1-ethyl-6-fluoro-4-keto-quinoline-3-carboxylic acid | MLS000589332 | SMR000212831 | cid_3726683
Type:
Small organic molecule
Emp. Form.:
C19H16FN3O3
Mol. Mass.:
353.347
SMILES:
CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N=NCc1ccccc1 |w:17.18|
Structure:
Search PDB for entries with ligand similarity: