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Target
Trace amine-associated receptor 1
Ligand
BDBM96700
Substrate
n/a
IC50
2256±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96700
Synonyms:
3-chloranyl-5-(2-phenylethylamino)-1,2-thiazole-4-carbonitrile | 3-chloro-5-(2-phenylethylamino)-1,2-thiazole-4-carbonitrile | 3-chloro-5-(2-phenylethylamino)-4-isothiazolecarbonitrile | 3-chloro-5-(phenethylamino)-4-isothiazolecarbonitrile | 3-chloro-5-(phenethylamino)isothiazole-4-carbonitrile | MLS000696339 | SMR000337537 | cid_3787753
Type:
Small organic molecule
Emp. Form.:
C12H10ClN3S
Mol. Mass.:
263.746
SMILES:
Clc1nsc(NCCc2ccccc2)c1C#N
Structure:
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