Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96885
Substrate
n/a
IC50
1530±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96885
Synonyms:
(2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[(3,4-dichlorobenzoyl)amino]-3-methyl-butanoyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[(3,4-dichlorobenzoyl)amino]-3-methylbutanoyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[(3,4-dichlorophenyl)carbonylamino]-3-methyl-butanoyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[[(3,4-dichlorophenyl)-oxomethyl]amino]-3-methyl-1-oxobutyl]-2-pyrrolidinecarboxamide | MLS003777924 | SMR002440904 | cid_53361926
Type:
Small organic molecule
Emp. Form.:
C25H28Cl3N3O3
Mol. Mass.:
524.867
SMILES:
CC(C)[C@H](NC(=O)c1ccc(Cl)c(Cl)c1)C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: