Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96925
Substrate
n/a
EC50
>29900±n/a nM
Citation
 PubChem, PC Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify TAAR1 Agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96925
Synonyms:
2-[(4-methylbenzyl)thio]-N-[5-morpholinosulfonyl-2-(2,2,2-trifluoroethoxy)phenyl]acetamide | 2-[(4-methylphenyl)methylsulfanyl]-N-[5-morpholin-4-ylsulfonyl-2-(2,2,2-trifluoroethoxy)phenyl]acetamide | 2-[(4-methylphenyl)methylsulfanyl]-N-[5-morpholin-4-ylsulfonyl-2-[2,2,2-tris(fluoranyl)ethoxy]phenyl]ethanamide | 2-[(4-methylphenyl)methylthio]-N-[5-(4-morpholinylsulfonyl)-2-(2,2,2-trifluoroethoxy)phenyl]acetamide | MLS002182285 | SMR001271315 | cid_25163212
Type:
Small organic molecule
Emp. Form.:
C22H25F3N2O5S2
Mol. Mass.:
518.57
SMILES:
Cc1ccc(CSCC(=O)Nc2cc(ccc2OCC(F)(F)F)S(=O)(=O)N2CCOCC2)cc1
Structure:
Search PDB for entries with ligand similarity: