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Target
Trace amine-associated receptor 1
Ligand
BDBM48687
Substrate
n/a
IC50
190.97±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM48687
Synonyms:
MLS000552475 | N-[1-(2,5-Dimethyl-1-p-tolyl-1H-pyrrol-3-yl)-meth-(E)-ylidene]-N'-(5-nitro-pyridin-2-yl)-hydrazine | N-[[2,5-dimethyl-1-(4-methylphenyl)-3-pyrrolyl]methylideneamino]-5-nitro-2-pyridinamine | N-[[2,5-dimethyl-1-(4-methylphenyl)pyrrol-3-yl]methylideneamino]-5-nitro-pyridin-2-amine | N-[[2,5-dimethyl-1-(4-methylphenyl)pyrrol-3-yl]methylideneamino]-5-nitropyridin-2-amine | SMR000145990 | [(E)-[2,5-dimethyl-1-(p-tolyl)pyrrol-3-yl]methyleneamino]-(5-nitro-2-pyridyl)amine | [[2,5-dimethyl-1-(p-tolyl)pyrrol-3-yl]methyleneamino]-(5-nitro-2-pyridyl)amine | cid_4516862
Type:
Small organic molecule
Emp. Form.:
C19H19N5O2
Mol. Mass.:
349.3865
SMILES:
Cc1cc(CN=Nc2ccc(cn2)[N+]([O-])=O)c(C)n1-c1ccc(C)cc1 |w:5.4|
Structure:
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