Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM97204
Substrate
n/a
IC50
>67486±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
  
Inhibitor
Name:
BDBM97204
Synonyms:
2-Methyl-furan-3-carboxylic acid (6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)-hydrazide | MLS000564428 | N-[(E)-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)amino]-2-methyl-3-furancarboxamide | N-[(E)-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)amino]-2-methyl-furan-3-carboxamide | N-[(E)-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)amino]-2-methylfuran-3-carboxamide | N-[(E)-(6-methoxytetralin-1-ylidene)amino]-2-methyl-3-furamide | SMR000176576 | cid_5727258
Type:
Small organic molecule
Emp. Form.:
C17H18N2O3
Mol. Mass.:
298.3364
SMILES:
COc1ccc2C(CCCc2c1)=NNC(=O)c1ccoc1C |w:12.14|
Structure:
Search PDB for entries with ligand similarity: