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Target
Reverse transcriptase protein
Ligand
BDBM99893
Substrate
n/a
Meas. Tech.
Enzyme Inhibition Assay
IC50
6.60e+3±n/a nM
Citation
 Bode, ML; Rousseau, AL; Gravestock, D; Moleele, SS; Van Der Westhuyzen, CW Imidazopyridines and imidazopyrimidines as HIV-1 reverse transcriptase inhibitors US Patent  US8501767 Publication Date 8/6/2013 
Target
Name:
Reverse transcriptase protein
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
30157.99
Organism:
Human immunodeficiency virus 1
Description:
Q9WJP9
Residue:
259
Sequence:
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKNSKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNRKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQK
  
Inhibitor
Name:
BDBM99893
Synonyms:
US8501767, 96
Type:
Small organic molecule
Emp. Form.:
C20H19ClN4
Mol. Mass.:
350.845
SMILES:
Clc1ccccc1-c1nc2ccc(cn2c1NC1CCCCC1)C#N
Structure:
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