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Target
Kallikrein-7
Ligand
BDBM100025
Substrate
n/a
EC50
>69511±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100025
Synonyms:
3-(2-furanylmethyl)-2-phenyl-1,2-dihydroquinazolin-4-one | 3-(2-furfuryl)-2-phenyl-1,2-dihydroquinazolin-4-one | 3-(furan-2-ylmethyl)-2-phenyl-1,2-dihydroquinazolin-4-one | MLS000113614 | SMR000109510 | cid_2928530
Type:
Small organic molecule
Emp. Form.:
C19H16N2O2
Mol. Mass.:
304.3425
SMILES:
O=C1N(Cc2ccco2)C(Nc2ccccc12)c1ccccc1
Structure:
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