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Target
Kallikrein-7
Ligand
BDBM100031
Substrate
n/a
EC50
5476±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100031
Synonyms:
MLS000527663 | N-(2,3-dimethyl-6-quinoxalinyl)-1-piperidinecarboxamide | N-(2,3-dimethylquinoxalin-6-yl)piperidine-1-carboxamide | Piperidine-1-carboxylic acid (2,3-dimethyl-quinoxalin-6-yl)-amide | SMR000120237 | cid_804520
Type:
Small organic molecule
Emp. Form.:
C16H20N4O
Mol. Mass.:
284.3562
SMILES:
Cc1nc2ccc(NC(=O)N3CCCCC3)cc2nc1C
Structure:
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