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Target
Kallikrein-7
Ligand
BDBM100058
Substrate
n/a
EC50
>7723±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100058
Synonyms:
MLS000718244 | N-cyclopentyl-2-(4-fluorophenyl)-3-imidazo[1,2-a]pyrazinamine | N-cyclopentyl-2-(4-fluorophenyl)imidazo[1,2-a]pyrazin-3-amine | SMR000290512 | cid_4114964 | cyclopentyl-[2-(4-fluorophenyl)imidazo[1,2-a]pyrazin-3-yl]amine
Type:
Small organic molecule
Emp. Form.:
C17H17FN4
Mol. Mass.:
296.3421
SMILES:
Fc1ccc(cc1)-c1nc2cnccn2c1NC1CCCC1
Structure:
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