Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM100070
Substrate
n/a
EC50
6338±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100070
Synonyms:
7-(diethylamino)-3-(hydroxymethyl)-4-methyl-1-benzopyran-2-one | 7-(diethylamino)-3-(hydroxymethyl)-4-methyl-2H-chromen-2-one | 7-(diethylamino)-3-(hydroxymethyl)-4-methyl-chromen-2-one | 7-(diethylamino)-3-(hydroxymethyl)-4-methylchromen-2-one | 7-(diethylamino)-4-methyl-3-methylol-coumarin | MLS000766701 | SMR000339597 | cid_747166
Type:
Small organic molecule
Emp. Form.:
C15H19NO3
Mol. Mass.:
261.3163
SMILES:
CCN(CC)c1ccc2c(C)c(CO)c(=O)oc2c1
Structure:
Search PDB for entries with ligand similarity: