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Target
Kallikrein-7
Ligand
BDBM100095
Substrate
n/a
EC50
1835±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100095
Synonyms:
2-Oxo-1,2-dihydro-benzo[cd]indole-6-sulfonic acid (2-dimethylamino-ethyl)-amide | MLS001202925 | N-[2-(dimethylamino)ethyl]-2-keto-1H-benzo[cd]indole-6-sulfonamide | N-[2-(dimethylamino)ethyl]-2-oxidanylidene-1H-benzo[cd]indole-6-sulfonamide | N-[2-(dimethylamino)ethyl]-2-oxo-1H-benzo[cd]indole-6-sulfonamide | SMR000514193 | cid_1103358
Type:
Small organic molecule
Emp. Form.:
C15H17N3O3S
Mol. Mass.:
319.379
SMILES:
CN(C)CCNS(=O)(=O)c1ccc2NC(=O)c3cccc1c23
Structure:
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