Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM100103
Substrate
n/a
EC50
>2575±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100103
Synonyms:
3-(4-methoxyphenyl)-8-[(2-methylpiperidin-1-yl)methyl]-7-oxidanyl-chromen-4-one | 7-hydroxy-3-(4-methoxyphenyl)-8-[(2-methyl-1-piperidinyl)methyl]-1-benzopyran-4-one | 7-hydroxy-3-(4-methoxyphenyl)-8-[(2-methylpiperidin-1-yl)methyl]chromen-4-one | 7-hydroxy-3-(4-methoxyphenyl)-8-[(2-methylpiperidino)methyl]chromone | MLS001214851 | SMR000543352 | cid_5778780
Type:
Small organic molecule
Emp. Form.:
C23H25NO4
Mol. Mass.:
379.4489
SMILES:
COc1ccc(cc1)-c1coc2c(CN3CCCCC3C)c(O)ccc2c1=O
Structure:
Search PDB for entries with ligand similarity: