Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM81149
Substrate
n/a
EC50
>2574±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM81149
Synonyms:
MLS001213181 | N'-(10H-indolo[3,2-b]quinolin-2-yl)-N,N-dimethyl-methanimidamide | N'-(10H-indolo[3,2-b]quinolin-2-yl)-N,N-dimethylmethanimidamide | N,N-dimethyl-N'-(10H-quindolin-2-yl)formamidine | SMR000542853 | cid_2882843
Type:
Small organic molecule
Emp. Form.:
C18H16N4
Mol. Mass.:
288.3464
SMILES:
CN(C)C=Nc1ccc2nc3c(cc2c1)[nH]c1ccccc31 |w:4.4|
Structure:
Search PDB for entries with ligand similarity: