Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM83808
Substrate
n/a
EC50
16488±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM83808
Synonyms:
5-bromanyl-6-oxidanylidene-N-(2-phenylethyl)pyran-3-carboxamide | 5-bromo-6-keto-N-phenethyl-pyran-3-carboxamide | 5-bromo-6-oxo-N-(2-phenylethyl)-3-pyrancarboxamide | 5-bromo-6-oxo-N-(2-phenylethyl)pyran-3-carboxamide | MLS001164989 | SMR000540280 | cid_930668
Type:
Small organic molecule
Emp. Form.:
C14H12BrNO3
Mol. Mass.:
322.154
SMILES:
Brc1cc(coc1=O)C(=O)NCCc1ccccc1
Structure:
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