Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM100118
Substrate
n/a
EC50
5160±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100118
Synonyms:
2-(2-keto-3-phenyl-chromen-7-yl)oxypropionic acid methyl ester | 2-[(2-oxo-3-phenyl-1-benzopyran-7-yl)oxy]propanoic acid methyl ester | MLS001167026 | SMR000641318 | cid_16450243 | methyl 2-(2-oxidanylidene-3-phenyl-chromen-7-yl)oxypropanoate | methyl 2-(2-oxo-3-phenylchromen-7-yl)oxypropanoate
Type:
Small organic molecule
Emp. Form.:
C19H16O5
Mol. Mass.:
324.3273
SMILES:
COC(=O)C(C)Oc1ccc2cc(-c3ccccc3)c(=O)oc2c1
Structure:
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