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Target
Kallikrein-7
Ligand
BDBM100129
Substrate
n/a
EC50
8312±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100129
Synonyms:
MLS001223360 | N-[4-[2-(2-chloranylphenoxy)ethanoylamino]-2-methoxy-phenyl]thiophene-2-carboxamide | N-[4-[[2-(2-chlorophenoxy)-1-oxoethyl]amino]-2-methoxyphenyl]-2-thiophenecarboxamide | N-[4-[[2-(2-chlorophenoxy)acetyl]amino]-2-methoxy-phenyl]thiophene-2-carboxamide | N-[4-[[2-(2-chlorophenoxy)acetyl]amino]-2-methoxyphenyl]thiophene-2-carboxamide | SMR000613163 | Thiophene-2-carboxylic acid {4-[2-(2-chloro-phenoxy)-acetylamino]-2-methoxy-phenyl}-amide | cid_3161506
Type:
Small organic molecule
Emp. Form.:
C20H17ClN2O4S
Mol. Mass.:
416.878
SMILES:
COc1cc(NC(=O)COc2ccccc2Cl)ccc1NC(=O)c1cccs1
Structure:
Search PDB for entries with ligand similarity: