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Target
Kallikrein-7
Ligand
BDBM83150
Substrate
n/a
EC50
>23168±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM83150
Synonyms:
6-(4-mesylphenyl)-N-morpholino-thieno[2,3-f][1,3]benzodioxole-7-carboxamide | 6-(4-methylsulfonylphenyl)-N-(4-morpholinyl)-7-thieno[2,3-f][1,3]benzodioxolecarboxamide | 6-(4-methylsulfonylphenyl)-N-morpholin-4-yl-thieno[2,3-f][1,3]benzodioxole-7-carboxamide | 6-(4-methylsulfonylphenyl)-N-morpholin-4-ylthieno[2,3-f][1,3]benzodioxole-7-carboxamide | MLS002473584 | SMR001397751 | cid_44202232
Type:
Small organic molecule
Emp. Form.:
C21H20N2O6S2
Mol. Mass.:
460.523
SMILES:
CS(=O)(=O)c1ccc(cc1)-c1sc2cc3OCOc3cc2c1C(=O)NN1CCOCC1
Structure:
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