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Target
Kallikrein-7
Ligand
BDBM100164
Substrate
n/a
EC50
7952±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100164
Synonyms:
MLS002582724 | N-[3-cyano-1-(2-furanylmethyl)-10-methyl-5-oxo-2-dipyrido[3,4-c:1',2'-f]pyrimidinylidene]benzamide | N-[3-cyano-1-(2-furfuryl)-5-keto-10-methyl-dipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]benzamide | N-[3-cyano-1-(furan-2-ylmethyl)-10-methyl-5-oxidanylidene-dipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]benzamide | N-[3-cyano-1-(furan-2-ylmethyl)-10-methyl-5-oxodipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]benzamide | SMR001496657 | cid_663304
Type:
Small organic molecule
Emp. Form.:
C25H17N5O3
Mol. Mass.:
435.4342
SMILES:
Cc1cccn2c1nc1n(Cc3ccco3)\c(=N\C(=O)c3ccccc3)c(cc1c2=O)C#N
Structure:
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