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Target
Kallikrein-7
Ligand
BDBM46572
Substrate
n/a
EC50
>7722±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM46572
Synonyms:
(6E)-5-azanylidene-6-[(4-oxidanylidenechromen-3-yl)methylidene]-2-pyridin-4-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | (6E)-5-imino-6-[(4-ketochromen-3-yl)methylene]-2-(4-pyridyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | (6E)-5-imino-6-[(4-oxo-1-benzopyran-3-yl)methylidene]-2-pyridin-4-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | (6E)-5-imino-6-[(4-oxochromen-3-yl)methylidene]-2-pyridin-4-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | 5-Imino-6-[1-(4-oxo-4H-chromen-3-yl)-meth-(E)-ylidene]-2-pyridin-4-yl-5,6-dihydro-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | MLS000331964 | SMR000221531 | cid_1976446
Type:
Small organic molecule
Emp. Form.:
C20H11N5O3S
Mol. Mass.:
401.398
SMILES:
N=C1N2N=C(SC2=NC(=O)\C1=C\c1coc2ccccc2c1=O)c1ccncc1 |c:3,7|
Structure:
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