Reaction Details
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Report a problem with these dataTarget
COUP transcription factor 2
Ligand
BDBM77198
Substrate
n/a
IC50
4976±n/a nM
Citation
PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
Inhibitor
Name:
BDBM77198
Synonyms:
5,6-dimethyl-4-[4-[2-(4-methylphenoxy)ethyl]-1-piperazinyl]thieno[2,3-d]pyrimidine | 5,6-dimethyl-4-[4-[2-(4-methylphenoxy)ethyl]piperazin-1-yl]thieno[2,3-d]pyrimidine | 5,6-dimethyl-4-[4-[2-(4-methylphenoxy)ethyl]piperazino]thieno[2,3-d]pyrimidine | 5,6-dimethyl-4-{4-[2-(4-methylphenoxy)ethyl]-1-piperazinyl}thieno[2,3-d]pyrimidine | MLS000537743 | SMR000143981 | cid_1999904
Type:
Small organic molecule
Emp. Form.:
C21H26N4OS
Mol. Mass.:
382.522
SMILES:
Cc1sc2ncnc(N3CCN(CCOc4ccc(C)cc4)CC3)c2c1C
Structure:
