Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM100206
Substrate
n/a
IC50
8413±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM100206
Synonyms:
4-(2-methyl-3-imidazo[1,2-a]pyridinyl)-N-(3-methylphenyl)-2-thiazolamine | 4-(2-methylimidazo[1,2-a]pyridin-3-yl)-N-(3-methylphenyl)-1,3-thiazol-2-amine | MLS000579062 | SMR000186651 | [4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-yl]-(m-tolyl)amine | cid_704682
Type:
Small organic molecule
Emp. Form.:
C18H16N4S
Mol. Mass.:
320.411
SMILES:
Cc1nc2ccccn2c1-c1csc(Nc2cccc(C)c2)n1
Structure:
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