Reaction Details
Report a problem with these data
Report a problem with these dataTarget
COUP transcription factor 2
Ligand
BDBM100234
Substrate
n/a
IC50
10652±n/a nM
Citation
PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
Inhibitor
Name:
BDBM100234
Synonyms:
4-chloranyl-5,6-dimethyl-7-(phenylmethyl)pyrrolo[2,3-d]pyrimidine | 4-chloro-5,6-dimethyl-7-(phenylmethyl)pyrrolo[2,3-d]pyrimidine | 7-benzyl-4-chloro-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine | 7-benzyl-4-chloro-5,6-dimethyl-pyrrolo[2,3-d]pyrimidine | 7-benzyl-4-chloro-5,6-dimethylpyrrolo[2,3-d]pyrimidine | MLS001195354 | SMR000550587 | cid_1475476
Type:
Small organic molecule
Emp. Form.:
C15H14ClN3
Mol. Mass.:
271.745
SMILES:
Cc1c(C)c2c(Cl)ncnc2n1Cc1ccccc1
Structure:
