Reaction Details Report a problem with these data
Target
Cathepsin L2
Ligand
BDBM103349
Substrate
n/a
Meas. Tech.
In Vitro Inhibition Assay
Ki
1900±0.0 nM
Citation
 Quibell, M; Watts, JP; Flinn, NS Furo[3, 2-B] pyrrol-3-ones as cathespin S inhibitors US Patent  US8552202 Publication Date 10/8/2013 
Target
Name:
Cathepsin L2
Synonyms:
CATL2 | CATL2_HUMAN | CTSL2 | CTSU | CTSV | Cathepsin U | Cathepsin V
Type:
Enzyme
Mol. Mass.:
37341.06
Organism:
Homo sapiens (Human)
Description:
O60911
Residue:
334
Sequence:
MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
  
Inhibitor
Name:
BDBM103349
Synonyms:
US8552202, Compound 1
Type:
Small organic molecules
Emp. Form.:
C21H26N2O4
Mol. Mass.:
370.4421
SMILES:
O=C(N[C@@H](C1CCCCC1)C(=O)N1CC[C@H]2OCC(=O)[C@@H]12)c1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: