Reaction Details Report a problem with these data
Target
Group 3 secretory phospholipase A2
Ligand
BDBM83283
Substrate
n/a
Meas. Tech.
QFRET-based biochemical high throughput dose response assay to identify inhibitors of human group III secreted phospholipase A2 enzyme (HGIII-sPLA2)
IC50
121867±n/a nM
Citation
 PubChem, PC QFRET-based biochemical high throughput dose response assay to identify inhibitors of human group III secreted phospholipase A2 enzyme (HGIII-sPLA2) PubChem Bioassay (2014)[AID] 
Target
Name:
Group 3 secretory phospholipase A2
Synonyms:
3.1.1.4 | GIII sPLA2 | Group III secretory phopholipase A2 | Group III secretory phospholipase A2 | PA2G3_HUMAN | PLA2G3 | Phosphatidylcholine 2-acylhydrolase 3 | phospholipase A2, group III | sPLA2-III
Type:
PROTEIN
Mol. Mass.:
57196.58
Organism:
Homo sapiens
Description:
ChEMBL_119722
Residue:
509
Sequence:
MGVQAGLFGMLGFLGVALGGSPALRWYRTSCHLTKAVPGNPLGYLSFLAKDAQGLALIHARWDAHRRLQSCSWEDEPELTAAYGALCAHETAWGSFIHTPGPELQRALATLQSQWEACRALEESPAGARKKRAAGQSGVPGGGHQREKRGWTMPGTLWCGVGDSAGNSSELGVFQGPDLCCREHDRCPQNISPLQYNYGIRNYRFHTISHCDCDTRFQQCLQNQHDSISDIVGVAFFNVLEIPCFVLEEQEACVAWYWWGGCRMYGTVPLARLQPRTFYNASWSSRATSPTPSSRSPAPPKPRQKQHLRKGPPHQKGSKRPSKANTTALQDPMVSPRLDVAPTGLQGPQGGLKPQGARWVCRSFRRHLDQCEHQIGPREIEFQLLNSAQEPLFHCNCTRRLARFLRLHSPPEVTNMLWELLGTTCFKLAPPLDCVEGKNCSRDPRAIRVSARHLRRLQQRRHQLQDKGTDERQPWPSEPLRGPMSFYNQCLQLTQAARRPDRQQKSWSQ
  
Inhibitor
Name:
BDBM83283
Synonyms:
MLS002920361 | N-(3-chloro-1,4-diketo-2-naphthyl)-N-(2-methoxyphenyl)acetamide | N-(3-chloro-1,4-dioxo-2-naphthalenyl)-N-(2-methoxyphenyl)acetamide | N-(3-chloro-1,4-dioxonaphthalen-2-yl)-N-(2-methoxyphenyl)acetamide | N-[3-chloranyl-1,4-bis(oxidanylidene)naphthalen-2-yl]-N-(2-methoxyphenyl)ethanamide | SMR001797954 | cid_282598
Type:
Small organic molecule
Emp. Form.:
C19H14ClNO4
Mol. Mass.:
355.772
SMILES:
COc1ccccc1N(C(C)=O)C1=C(Cl)C(=O)c2ccccc2C1=O |c:13|
Structure:
Search PDB for entries with ligand similarity: