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Target
Mu-type opioid receptor
Ligand
BDBM114620
Substrate
n/a
Meas. Tech.
Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50
92470±n/a nM
Citation
 PubChem, PC Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay to identify agonists of the mu 1 opioid receptor (OPRM1) PubChem Bioassay (2013)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM114620
Synonyms:
1-[2-(2,3-dichlorophenoxy)ethyl]-3,5-dimethyl-piperidine | 1-[2-(2,3-dichlorophenoxy)ethyl]-3,5-dimethylpiperidine | 1-[2-[2,3-bis(chloranyl)phenoxy]ethyl]-3,5-dimethyl-piperidine | SR-01000719482 | SR-01000719482-2 | cid_2934438
Type:
Small organic molecule
Emp. Form.:
C15H21Cl2NO
Mol. Mass.:
302.239
SMILES:
CC1CC(C)CN(CCOc2cccc(Cl)c2Cl)C1
Structure:
Search PDB for entries with ligand similarity: