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Target
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Ligand
BDBM122998
Substrate
n/a
Meas. Tech.
Enzymatic Assay
IC50
0.995±n/a nM
Citation
 Stranix, BR; Lavallee, J; Leberre, N; Perron, V; Herbart, D; Milot, G; Panchal, C Protease inhibitors US Patent  US8742158 Publication Date 6/3/2014 
Target
Name:
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Synonyms:
HIV-1 protease | HIV-1 protease (G48V) | HIV-1 protease (V82A) | POL_HV1N5 | gag-pol
Type:
Protein
Mol. Mass.:
10827.77
Organism:
Human immunodeficiency virus
Description:
P12497[489-587,G537V,H558K,V571A]
Residue:
99
Sequence:
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYDQILIEICGKKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM122998
Synonyms:
US8742158, EX 15
Type:
Small organic molecule
Emp. Form.:
C36H48N4O5S
Mol. Mass.:
648.855
SMILES:
CC(C)CN(Sc1ccc2OCCc2c1)[C@H](CO)CCCCNC(=O)[C@@H](Cc1cccc2ccccc12)NC(=O)N1CCOCC1 |r|
Structure:
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