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Target
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Ligand
BDBM123010
Substrate
n/a
Meas. Tech.
Enzymatic Assay
IC50
1.353±n/a nM
Citation
 Stranix, BR; Lavallee, J; Leberre, N; Perron, V; Herbart, D; Milot, G; Panchal, C Protease inhibitors US Patent  US8742158 Publication Date 6/3/2014 
Target
Name:
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Synonyms:
HIV-1 protease | HIV-1 protease (G48V) | HIV-1 protease (V82A) | POL_HV1N5 | gag-pol
Type:
Protein
Mol. Mass.:
10827.77
Organism:
Human immunodeficiency virus
Description:
P12497[489-587,G537V,H558K,V571A]
Residue:
99
Sequence:
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYDQILIEICGKKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM123010
Synonyms:
US8742138, 38 | US8742158, EX 22
Type:
Small organic molecule
Emp. Form.:
C20H14F3NO6
Mol. Mass.:
421.3235
SMILES:
C[C@H](NC(=O)c1c2c(cccc2c(O)oc1=O)-c1cccc(c1)C(F)(F)F)C(O)=O
Structure:
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