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Target
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Ligand
BDBM123002
Substrate
n/a
Meas. Tech.
Enzymatic Assay
IC50
0.899±n/a nM
Citation
 Stranix, BR; Lavallee, J; Leberre, N; Perron, V; Herbart, D; Milot, G; Panchal, C Protease inhibitors US Patent  US8742158 Publication Date 6/3/2014 
Target
Name:
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Synonyms:
HIV-1 protease | HIV-1 protease (G48V) | HIV-1 protease (V82A) | POL_HV1N5 | gag-pol
Type:
Protein
Mol. Mass.:
10827.77
Organism:
Human immunodeficiency virus
Description:
P12497[489-587,G537V,H558K,V571A]
Residue:
99
Sequence:
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYDQILIEICGKKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM123002
Synonyms:
US8742158, EX 32
Type:
Small organic molecule
Emp. Form.:
C35H47N3O7S
Mol. Mass.:
653.829
SMILES:
COC(=O)N[C@@H](C(C1=CC=CCC1)c1ccccc1)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc2OCCc2c1 |r,c:9,t:7|
Structure:
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