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Target
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Ligand
BDBM122984
Substrate
n/a
Meas. Tech.
Enzymatic Assay
IC50
1.08±n/a nM
Citation
 Stranix, BR; Lavallee, J; Leberre, N; Perron, V; Herbart, D; Milot, G; Panchal, C Protease inhibitors US Patent  US8742158 Publication Date 6/3/2014 
Target
Name:
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Synonyms:
HIV-1 protease | HIV-1 protease (G48V) | HIV-1 protease (V82A) | POL_HV1N5 | gag-pol
Type:
Protein
Mol. Mass.:
10827.77
Organism:
Human immunodeficiency virus
Description:
P12497[489-587,G537V,H558K,V571A]
Residue:
99
Sequence:
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYDQILIEICGKKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM122984
Synonyms:
US8742158, EX. 10
Type:
Small organic molecule
Emp. Form.:
C33H43N5O6S
Mol. Mass.:
637.789
SMILES:
COC(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)NCCCCC(N(CC(C)C)S(=O)(=O)c1ccc(N)cc1)C(N)=O |r|
Structure:
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