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Target
D(3) dopamine receptor
Ligand
BDBM123840
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
1.1±n/a nM
IC50
1.2±n/a nM
Citation
 Newman, AH; Grundt, P; Cyriac, GC; Luedtke, R; Cao, J 4-phenylpiperazine derivatives with functionalized linkers as dopamine D3 receptor selective ligands and methods of use US Patent  US8748608 Publication Date 6/10/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM123840
Synonyms:
US8748608, 12
Type:
Small organic molecule
Emp. Form.:
C26H27Cl2N4O2
Mol. Mass.:
498.424
SMILES:
O[N]1=C(C=CC=C1)c1ccc(cc1)C(=O)NC\C=C\CN1CCN(CC1)c1cccc(Cl)c1Cl |c:3,5,t:1|
Structure:
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