Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 7b
Ligand
BDBM129500
Substrate
n/a
Meas. Tech.
Radioligand Binding
pH
7.4±n/a
Temperature
310.15±n/a K
Ki
14.6±n/a nM
Comments
extracted
Citation
 Galley, G; Norcross, RD; Pflieger, P Heterocyclic amine derivatives US Patent  US8802673 Publication Date 8/12/2014 
Target
Name:
Trace amine-associated receptor 7b
Synonyms:
TAA7B_RAT | Ta12 | Taar7b | Tar12 | Trace amine-associated receptor 1 (TAAR1) | Trar12
Type:
Enzyme
Mol. Mass.:
40296.65
Organism:
Rattus norvegicus (Rat)
Description:
Q923X8
Residue:
358
Sequence:
MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
  
Inhibitor
Name:
BDBM129500
Synonyms:
US8802673, 142
Type:
Small organic molecule
Emp. Form.:
C22H24N4O3
Mol. Mass.:
392.451
SMILES:
COc1ccc(cc1OC)-c1cnc(Nc2ccc(cc2)[C@@H]2CNCCO2)nc1 |r|
Structure:
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