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Target
D(3) dopamine receptor
Ligand
BDBM138490
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
3.65±n/a nM
Citation
 Rodriguez Sarmiento, RM; Wichmann, J Benzofurane compounds US Patent  US8877778 Publication Date 11/4/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM138490
Synonyms:
US8877778, 94
Type:
Small organic molecule
Emp. Form.:
C30H38N2O4
Mol. Mass.:
490.6337
SMILES:
O=C(Cc1ccc2OCOc2c1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 |r,wU:13.14,wD:16.18,(4.56,-.09,;5.33,1.24,;6.87,1.24,;7.64,-.09,;6.87,-1.43,;7.64,-2.76,;9.18,-2.76,;10.21,-3.91,;11.61,-3.28,;11.45,-1.75,;9.95,-1.43,;9.18,-.09,;4.56,2.57,;3.02,2.57,;2.25,1.24,;.71,1.24,;-.06,2.57,;-1.6,2.57,;-2.37,1.24,;-3.91,1.24,;-4.68,-.09,;-6.22,-.09,;-6.99,1.24,;-6.22,2.57,;-4.68,2.57,;-8.53,1.24,;-9.3,2.57,;-10.84,2.57,;-11.61,1.24,;-10.84,-.09,;-11.32,-1.56,;-10.07,-2.46,;-8.83,-1.56,;-9.3,-.09,;.71,3.91,;2.25,3.91,)|
Structure:
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