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Target
D(3) dopamine receptor
Ligand
BDBM141787
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
2.75±n/a nM
Citation
 Rodriguez Sarmiento, RM; Wichmann, J Benzofurane-piperidine compounds US Patent  US8921397 Publication Date 12/30/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM141787
Synonyms:
US8921397, 29
Type:
Small organic molecule
Emp. Form.:
C27H38N2O3
Mol. Mass.:
438.6022
SMILES:
O=C(CC1CCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 |r,wU:12.13,wD:9.9,(6.03,2.67,;6.8,1.33,;8.34,1.33,;9.11,,;10.57,-.48,;10.57,-2.02,;9.11,-2.49,;8.2,-1.25,;6.03,,;4.49,,;3.72,1.33,;2.18,1.33,;1.41,,;-.13,,;-.9,-1.33,;-2.44,-1.33,;-3.21,-2.67,;-4.75,-2.67,;-5.52,-1.33,;-4.75,,;-3.21,,;-7.06,-1.33,;-7.97,-2.58,;-9.43,-2.1,;-9.43,-.56,;-10.57,.47,;-10.25,1.97,;-8.79,2.45,;-7.65,1.42,;-7.97,-.09,;2.18,-1.33,;3.72,-1.33,)|
Structure:
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