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Target
Opioid growth factor receptor-like protein 1
Ligand
BDBM150219
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Temperature
323.15±n/a K
Ki
2.04±n/a nM
Comments
extracted
Citation
 Tafesse, L Pyridonemorphinan analogs and biological activity on opioid receptors US Patent  US8980906 Publication Date 3/17/2015 
Target
Name:
Opioid growth factor receptor-like protein 1
Synonyms:
OGFRL1 | OGRL1_HUMAN | Opioid Receptor-Like Receptor (ORL-1) | Opioid growth factor receptor-like protein 1 (ORL-1) | Opioid growth factor receptor-like protein 1 (ORL1) | Opioid receptor-like (ORL-1) | Opioid receptor-like (ORL1) | Opioid receptor-like protein 1 (OGL1) | Opioid receptor-like receptor (ORL1)
Type:
Protein
Mol. Mass.:
51247.53
Organism:
Homo sapiens (Human)
Description:
Q5TC84
Residue:
451
Sequence:
MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGGSEGPGQESEQPAQPPEQAGGRPGASPAPDEDAEAAGAEQGGDSTEATAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLSKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLTDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPRKEQSEGSKAQKMSSPLASSHNSQTSMHKKAKDSKNSSSAVHLNSKTAEDKKVAPKEPVEETDRPSPEPSNEAAKPRNTEKDSNAENMNSQPEKTVTTPTEKKESVSPENNEEGGNDNQDNENPGNTNCHDVVLVQ
  
Inhibitor
Name:
BDBM150219
Synonyms:
US8980906, 21
Type:
Small organic molecule
Emp. Form.:
C26H30N4O4
Mol. Mass.:
462.5408
SMILES:
NC(=O)CNC(=O)c1cc2C[C@H]3[C@H]4Cc5ccc(O)cc5[C@@]3(CCN4CC3CC3)Cc2[nH]c1=O |r|
Structure:
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