Reaction Details Report a problem with these data
Target
Alpha-synuclein
Ligand
BDBM170544
Substrate
n/a
Meas. Tech.
Competitive Binding Assay
pH
7.4±n/a
Ki
537±n/a nM
Comments
extracted
Citation
 Luke, EA; Yadon, MC; Cummings, J; Hudson, FM; Lake, T; Hu, Q; Cam, J; Snow, AD Compounds for the treatment of neurodegenerative diseases US Patent  US9085549 Publication Date 7/21/2015 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM170544
Synonyms:
US9085549, 79
Type:
Small organic molecule
Emp. Form.:
C25H37NO4SSn
Mol. Mass.:
566.34
SMILES:
CCCC[Sn](CCCC)(CCCC)c1cnc(s1)-c1ccc(OC(C)=O)c(OC(C)=O)c1
Structure:
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