Reaction Details Report a problem with these data
Target
Alpha-synuclein
Ligand
BDBM170572
Substrate
n/a
Meas. Tech.
Competitive Binding Assay
pH
7.4±n/a
Ki
1350±n/a nM
Comments
extracted
Citation
 Luke, EA; Yadon, MC; Cummings, J; Hudson, FM; Lake, T; Hu, Q; Cam, J; Snow, AD Compounds for the treatment of neurodegenerative diseases US Patent  US9085549 Publication Date 7/21/2015 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM170572
Synonyms:
US9085549, 96
Type:
Small organic molecule
Emp. Form.:
C15H11BrO5
Mol. Mass.:
351.149
SMILES:
Oc1ccc(\C=C\C(=O)c2cc(O)c(O)cc2Br)cc1O
Structure:
Search PDB for entries with ligand similarity: