Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM181010
Substrate
n/a
Meas. Tech.
Competition Binding Assay
pH
7.4±n/a
Ki
53±n/a nM
Comments
extracted
Citation
 Cabri, W; Minetti, P; Piersanti, G; Tarzia, G Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments US Patent  US9133197 Publication Date 9/15/2015 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM181010
Synonyms:
US9133197, 1
Type:
Small organic molecule
Emp. Form.:
C12H16N8O
Mol. Mass.:
288.3084
SMILES:
Cn1c(nc2c(N)nc(CCCCO)nc12)-n1nccn1
Structure:
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