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Target
Serine/threonine-protein kinase 16
Ligand
BDBM185152
Substrate
n/a
Meas. Tech.
Invitrogen SelectScreen Enzymatic Assay
IC50
295±0.0 nM
Citation
 Liu, F; Wang, J; Yang, X; Li, B; Wu, H; Qi, S; Chen, C; Liu, X; Yu, K; Wang, W; Zhao, Z; Wang, A; Chen, Y; Wang, L; Gray, NS; Liu, J; Zhang, X; Liu, Q Discovery of a Highly Selective STK16 Kinase Inhibitor. ACS Chem Biol 11:1537-43 (2016) [PubMed]  Article 
Target
Name:
Serine/threonine-protein kinase 16
Synonyms:
MPSK1 | PKL12 | STK16 | STK16_HUMAN | Serine/threonine-protein kinase 16 | TSF1 | Tyrosine-protein kinase STK16 (STK16)
Type:
Protein
Mol. Mass.:
34659.07
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
305
Sequence:
MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQHTTQI
  
Inhibitor
Name:
BDBM185152
Synonyms:
STK16-IN-1
Type:
Small organic molecule
Emp. Form.:
C16H10FN3O2
Mol. Mass.:
295.2679
SMILES:
Oc1cc(ccc1F)-n1c2c3cc[nH]c3ncc2ccc1=O
Structure:
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