Reaction Details Report a problem with these data
Target
Beta-galactosidase
Ligand
BDBM192770
Substrate
n/a
Meas. Tech.
beta-Galactosidase Assay
Temperature
303.15±n/a K
Ki
7.6e+4± 1e+3 nM
Comments
extracted
Citation
 Van Dyke, AR; Etemad, LS; Vessicchio, MJ; Naclerio, GA; Jedson, V Capture-Tag-Release: A Strategy for Small Molecule Labeling of Native Enzymes. Chembiochem 17:1602-5 (2016) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
BGAL_ECOLI | Beta-galactosidase | beta-Galactosidase (β-gal) | lacZ
Type:
Protein
Mol. Mass.:
116458.31
Organism:
Escherichia coli (Enterobacteria)
Description:
P00722
Residue:
1024
Sequence:
MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK
  
Inhibitor
Name:
BDBM192770
Synonyms:
IPTG
Type:
Small organic molecule
Emp. Form.:
C9H18O5S
Mol. Mass.:
238.301
SMILES:
CC(C)S[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
Structure:
Search PDB for entries with ligand similarity: