Reaction Details Report a problem with these data
Target
C-X-C chemokine receptor type 4
Ligand
BDBM194570
Substrate
n/a
Meas. Tech.
Competitive Binding Assay
IC50
1±n/a nM
Citation
 Natchus, MG; Arrendale, R; Liotta, D Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction US Patent  US9205085 Publication Date 12/8/2015 
Target
Name:
C-X-C chemokine receptor type 4
Synonyms:
C-X-C chemokine receptor type 4 | C-X-C chemokine receptor type 4 (CXCR4/SDF-1) | CXCR4_RAT | Cmkar4 | Cxcr4
Type:
Enzyme
Mol. Mass.:
39342.13
Organism:
Rattus norvegicus (Rat)
Description:
O08565
Residue:
349
Sequence:
MEIYTSDNYSEEVGSGDYDSNKEPCFRDENENFNRIFLPTIYFIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAMADWYFGKFLCKAVHIIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKAVYVGVWIPALLLTIPDIIFADVSQGDGRYICDRLYPDSLWMVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYVGISIDSFILLEVIKQGCEFESVVHKWISITEALAFFHCCLNPILYAFLGAKFKSSAQHALNSMSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
  
Inhibitor
Name:
BDBM194570
Synonyms:
US9205085, MSX- 203
Type:
Small organic molecule
Emp. Form.:
C20H18N4O4
Mol. Mass.:
378.3813
SMILES:
[O-][N+](=O)c1cccc(NCc2ccc(CNc3cccc(c3)[N+]([O-])=O)cc2)c1
Structure:
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