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Target
Serine/threonine-protein kinase pim-2
Ligand
BDBM119398
Substrate
n/a
Meas. Tech.
Pim Kinase Binding Activity
pH
7.2±n/a
Temperature
298.15±n/a K
Ki
0.167±n/a nM
Comments
extracted
Citation
 Wang, X Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use US Patent  US9573943 Publication Date 2/21/2017 
Target
Name:
Serine/threonine-protein kinase pim-2
Synonyms:
PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2)
Type:
Serine/threonine-protein kinase
Mol. Mass.:
34185.93
Organism:
Homo sapiens (Human)
Description:
Q9P1W9
Residue:
311
Sequence:
MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP
  
Inhibitor
Name:
BDBM119398
Synonyms:
US8669361, 140 | US9573943, Example 140
Type:
Small organic molecule
Emp. Form.:
C20H23F2N7OS
Mol. Mass.:
447.505
SMILES:
Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CCC[C@@H](N)CC1 |r|
Structure:
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