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Target
APC family lysine-specific permease
Ligand
BDBM217368
Substrate
n/a
Meas. Tech.
Isothermal Titration Calorimetry (ITC)
pH
5.9±0
Temperature
293.15±0 K
Kd
1.800e+6±n/a nM
Citation
 Kaur, J; Olkhova, E; Malviya, VN; Grell, E; Michel, H A L-lysine transporter of high stereoselectivity of the amino acid-polyamine-organocation (APC) superfamily: production, functional characterization, and structure modeling. J Biol Chem 289:1377-87 (2014) [PubMed]  Article 
Target
Name:
APC family lysine-specific permease
Synonyms:
LysP-related transporter STM2200 (STM2200)
Type:
Protein
Mol. Mass.:
53691.96
Organism:
Salmonella typhimurium
Description:
Q8ZNK9
Residue:
489
Sequence:
MGSKTKTTEAPALRRELKARHLTMIAIGGSIGTGLFVASGATISQAGPGGALFSYILIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNYWYNWAVTIAVDLVAAQLVMGWWFPDTPGWIWSALFLCVIFLLNYISVRGFGEAEYWFSLIKVATVIIFIIVGVAMIIGIFKGVEPVGWSNWTTGDAPFAGGFAAMIGVAMIVGFSFQGTELIGIAAGESENPEKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPNLLRNDVKDISVSPFTLVFQHAGLLSAAAIMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPRIFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAISHYRFRRGYVLQGYDVNDLPYRSGFFPLGPIFAFVLCLIITLGQNYEAFLKDTIDWGGVAATYIGIPLFLLIWFGYKLIKGTHFVRYSEMHFPERVKK
  
Inhibitor
Name:
BDBM217368
Synonyms:
(2R)-2,6-diaminohexanoic acid | D-Lysine
Type:
Small organic molecule
Emp. Form.:
C6H14N2O2
Mol. Mass.:
146.1876
SMILES:
NCCCC[C@@H](N)C(O)=O
Structure:
Search PDB for entries with ligand similarity: