Reaction Details Report a problem with these data
Target
Iodotyrosine deiodinase [1-228]
Ligand
BDBM217398
Substrate
n/a
Meas. Tech.
IYD Binding Assay
Kd
9.6e+4± 3e+3 nM
Citation
 Ingavat, N; Kavran, JM; Sun, Z; Rokita, SE Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase. Biochemistry 56:1130-1139 (2017) [PubMed]  Article 
Target
Name:
Iodotyrosine deiodinase [1-228]
Synonyms:
IYD | IYD_HALH1 | Iodotyrosine deiodinase (IYD)
Type:
Enzyme
Mol. Mass.:
26134.19
Organism:
Haliscomenobacter hydrossis
Description:
F4KU78[1-228]
Residue:
228
Sequence:
MKQKPAFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESYNGRMSNEWLEDLQPFGTDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYHHHHHH
  
Inhibitor
Name:
BDBM217398
Synonyms:
4-Amino-2-iodophenol (4A2IP)
Type:
Small organic molecule
Emp. Form.:
C6H6INO
Mol. Mass.:
235.0224
SMILES:
Nc1ccc(O)c(I)c1
Structure:
Search PDB for entries with ligand similarity: