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Target
Paired box protein Pax-2 [1-81]
Ligand
BDBM218809
Substrate
n/a
Meas. Tech.
Biolayer Interferometry Binding Assay
Kd
1.5e+3±n/a nM
Citation
Grimley, E; Liao, C; Ranghini, EJ; Nikolovska-Coleska, Z; Dressler, GR Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain. ACS Chem Biol 12:724-734 (2017) [PubMed] Article
More Info.:
Target
Name:
Paired box protein Pax-2 [1-81]
Synonyms:
PAX2 | PAX2_HUMAN | Paired box protein 2 (Pax2)
Type:
Protein
Mol. Mass.:
8841.67
Organism:
Homo sapiens (Human)
Description:
Human Pax2 (1-81 aa) containing the first DNA binding pocket defined in this study's homology model.
Residue:
81
Sequence:
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPG