Reaction Details Report a problem with these data
Target
3-phosphoinositide-dependent protein kinase 1 [409-556]
Ligand
BDBM223490
Substrate
n/a
Meas. Tech.
Silico Screening Assay
Kd
980±480 nM
Citation
Mahadevan, D; Meuillet, EJ; Mash, Jr., EA; Gokhale, VM; Powis, G; Zhang, S Small molecule inhibitors of the pleckstrin homology domain and methods for using same US Patent US9320734 Publication Date 4/26/2016
More Info.:
Target
Name:
3-phosphoinositide-dependent protein kinase 1 [409-556]
Synonyms:
3-phosphoinositide-dependent protein kinase 1 (PDK1) | PDK1 | PDPK1 | PDPK1_HUMAN
Type:
Enzyme
Mol. Mass.:
17526.67
Organism:
Human
Description:
PLECKSTRIN HOMOLOGY DOMAIN, RESIDUES 409-556 (PH domain)
Residue:
148
Sequence:
GSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ