Reaction Details Report a problem with these data
Target
Galectin-7
Ligand
BDBM223991
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
Temperature
277.15±0 K
Kd
9.0e+4± 3.5e+4 nM
Citation
 Dion, J; Deshayes, F; Storozhylova, N; Advedissian, T; Lambert, A; Viguier, M; Tellier, C; Dussouy, C; Poirier, F; Grandjean, C Lactosamine-Based Derivatives as Tools to Delineate the Biological Functions of Galectins: Application to Skin Tissue Repair. Chembiochem 18:782-789 (2017) [PubMed]  Article 
Target
Name:
Galectin-7
Synonyms:
Gal-7 | HKL-14 | LEG7_HUMAN | LGALS7 | PI7 | PIG1 | p53-induced gene 1 protein
Type:
Galactoside-binding protein
Mol. Mass.:
15077.89
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
136
Sequence:
MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF
  
Inhibitor
Name:
BDBM223991
Synonyms:
[3-O-(2-naphthyl)methyl-β-D-galactopyranosyl]-(1-4)-2-deoxy-2-(3-methoxybenzamido)-β-D-glucopyranoside (11)
Type:
Small organic molecule
Emp. Form.:
C34H41N3O12
Mol. Mass.:
683.7022
SMILES:
COc1cccc(c1)C(=O)CC1C(O)[C@H](O[C@@H]2OC(CO)[C@H](O)C(OCc3ccc4ccccc4c3)C2O)C(CO)O[C@H]1OCC[N-][N+]#N |r|
Structure:
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