Reaction Details Report a problem with these data
Target
Tyrosine-protein kinase SYK [355-635]
Ligand
BDBM225499
Substrate
n/a
Meas. Tech.
SYK assay_HTRF
IC50
849±n/a nM
Citation
 D3R, DD GSK SYK Kinase D3R 225:0 (2015) [PubMed] 
Target
Name:
Tyrosine-protein kinase SYK [355-635]
Synonyms:
KSYK_HUMAN | SYK | SYK Kinase
Type:
n/a
Mol. Mass.:
32610.83
Organism:
Homo sapiens (Human)
Description:
P43405[355-635]
Residue:
281
Sequence:
PEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
  
Inhibitor
Name:
BDBM225499
Synonyms:
GTC000208A
Type:
Small Organic Molecule
Emp. Form.:
C26H23N7O2
Mol. Mass.:
465.5065
SMILES:
COc1ccc(NC(=O)Cc2ccc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc2)cc1
Structure:
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