Target
SYK Kinase
Ligand
BDBM225520
Substrate
n/a
Meas. Tech.
SYK assay_HTRF
IC50
1.1±n/a nM
Citation
 D3R, DD GSK SYK Kinase D3R 225:0 (2015) [PubMed]
Target
Name:
SYK Kinase
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
32610.83
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
281
Sequence:
PEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
  
Inhibitor
Name:
BDBM225520
Synonyms:
GTC000228A | GTC000228B | GTC000228C
Type:
Small Organic Molecule
Emp. Form.:
C22H22FN7O3S
Mol. Mass.:
483.519
SMILES:
COCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CNS(=O)(=O)c3c2)ncc1F
Structure:
Search PDB for entries with ligand similarity: