Reaction Details Report a problem with these data
Target
Fatty acid-binding protein 5 [K24A,R33A,K34A]
Ligand
BDBM228800
Substrate
n/a
Meas. Tech.
Ligand Binding Assay
pH
8.2±n/a
Temperature
303.15±n/a K
Ki
1.24e+3±n/a nM
Comments
extracted
Citation
 Armstrong, EH; Goswami, D; Griffin, PR; Noy, N; Ortlund, EA Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor ß/d (FABP5-PPARß/d) signaling pathway. J Biol Chem 289:14941-54 (2014) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein 5 [K24A,R33A,K34A]
Synonyms:
FABP5 | FABP5_HUMAN | Fatty acid-binding protein 5 (FABP5)(NLSm)
Type:
Protein
Mol. Mass.:
14962.47
Organism:
Homo sapiens (Human)
Description:
Human FABP5 NLS-deficient mutant (K24A/K34A/R33A)
Residue:
135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMAELGVGIALAAMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE
  
Inhibitor
Name:
BDBM228800
Synonyms:
NOEV | Sapienic acid (SpA)
Type:
Small organic molecule
Emp. Form.:
C15H29NO4
Mol. Mass.:
287.3951
SMILES:
CCCCCCCCN[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |t:10|
Structure:
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